1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide
نویسندگان
چکیده
In the title compound, C(18)H(17)BrN(2)O(2), which is a potential -human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring exhibits an envelope conformation. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds [N⋯O = 2.861 (3) Å] link the mol-ecules into centrosymmetric dimers.
منابع مشابه
(S)-5-Oxo-N-phenylpyrrolidine-2-carboxamide
The title compound, C(11)H(12)N(2)O(2), shows an S configuration, in which the pyrrolidinone ring is twisted with respect to the phenyl plane, making a dihedral angle of 70.73 (7)°. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds, building up a layer parallel to (001).
متن کاملMethyl 2-benzyl-5-[1-(4-methoxyphenyl)-4-oxo-3-phenylazetidin-2-yl]-4-nitro-3-phenylpyrrolidine-2-carboxylate
In the title mol-ecule, C(35)H(33)N(3)O(6), the pyrrolidine ring adopts a twist conformation. The mol-ecules are paired into centrosymmetric dimers by weak inter-molecular C-H⋯O hydrogen bonds. The dimers inter-act further again via C-H⋯O hydrogen bonds and N-H⋯O intramolecular interaction also stabilize the crystal packing.
متن کاملN-(4-Bromobenzoyl)-N,N′-dicyclohexylurea
In the title compound, C(20)H(27)BrN(2)O(2), mol-ecules are linked into one-dimensional chains through (amide)N-H⋯O=C(amide) inter-molecular hydrogen bonds.
متن کاملcatena-Poly[[tetraaquacopper(II)]-μ-pyrazine-2-carboxamide-κ3 N 4:N 1,O-[bis(sulfato-κO)copper(II)]-μ-pyrazine-2-carboxamide-κ3 N 1,O:N 4]
In the crystal of the title polymeric compound, [Cu(2)(SO(4))(2)(C(5)H(5)N(3)O)(2)(H(2)O)(4)](n), two independent Cu(II) atoms are located on individual inversion centers. One Cu(II) atom is coordinated by four water mol-ecules and two pyrazine-2-carboxamide ligands in a distorted O(4)N(2) octa-hedral geometry; the other is N,O-chelated by two pyrazine-2-carboxamide ligands and further coordina...
متن کامل4-(Naphthalene-2-carboxamido)pyridin-1-ium thiocyanate–N-(pyridin-4-yl)naphthalene-2-carboxamide (1/1)
The asymmetric unit of the title compound, C(16)H(13)N(2)O(+)·NCS(-)·C(16)H(12)N(2)O, contains two N-(pyridin-4-yl)naphthalene-2-carboxamide mol-ecules, both are partially protonated in the pyridine moiety, i.e. the H atom attached to the pyridine N atom is partially occupied with an occupancy factor of 0.61 (3) and 0.39 (3), respectively. In the crystal, protonated and neutral N-(pyridin-4-yl)...
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عنوان ژورنال:
دوره 64 شماره
صفحات -
تاریخ انتشار 2008